Azarbaijan Shahid Madani University Journal of Applied Health Studies in Sport Physiology 2676-6507 6 1 2019 09 23 The Effect of Nonlinear Resistance Training with Supplementation of Spirulina on Serum Leptin and Ghrelin in Obese Women The Effect of Nonlinear Resistance Training with Supplementation of Spirulina on Serum Leptin and Ghrelin in Obese Women 69 77 13973 10.22049/jassp.2019.26662.1271 FA Rahele Kaka MSc of Exercise Physiology, Department of Sport Physiology, Faculty of Humanities, Lamerd Islamic Azad University, Lamerd, Iran. 0000-0002-3703-9772 Hadi Ghaedi Assistant Professor, Department of Sport Physiology, Faculty of Humanities, Lamerd Islamic Azad University, Lamerd, Iran. Sirous Farsi Assistant Professor, Department of Physical Education and Sport Sciences, larestan , Islamic Azad Of University, larestan, Iran Amir Taghipour Asrami Assistant Professor, Department of Physical Education and Sport Sciences, Ghaemshahr Technical and Vocational School, Ghaemshahr, Iran Journal Article 2019 06 10 Aim: Obesity is the greatest public health challenge in ages. The purpose of this study was to investigate the effect of nonlinear resistance training along with supplementation of Spirulina on serum Leptin and Ghrelin in obese women. Methods: A sample of 40 healthy obese women with body mass index BMI≥30 were selected through stratified sampling method. They were randomly assigned to four groups of nonlinear resistance training, Spirulina supplement, nonlinear resistance training + Spirulina supplementation and Placebo (n=10). Interventions were done for 8 weeks. 24 hours before and 48 hours after the end of the interventions, blood samples were taken from all four groups in a 12-hour fasting state. For each sample, leptin and Ghrelin serum levels were measured by ELISA method. The nonlinear resistance training program included exercising weight training at varying intensity, with emphasis on muscular endurance. Supplements and placebo daily consumed 2 capsules of 500 mg of Spirulina or starch. In order to compare and evaluate the variables in four groups of research and in two blood sampling times, the inter-interstitial analysis of variance analysis was used in a 4 × 2 test and the Tukey's test was used to find means that are significantly different from each other. Results: There was no significant change in the level of Ghrelin. Leptin levels decreased significantly in the two groups nonlinear resistance training + Spirulina supplementation and nonlinear resistance compared to the other two groups. There was no significant difference between the variables of the two nonlinear resistance training + Spirulina supplementation and nonlinear resistance training groups and between the variables of the two groups of Spirulina and placebo. Conclusions: Probably eight weeks of nonlinear resistance training will lead to improved fat metabolism in overweight and obesity-related diseases such as heart disease and diabetes in obese women. Aim: Obesity is the greatest public health challenge in ages. The purpose of this study was to investigate the effect of nonlinear resistance training along with supplementation of Spirulina on serum Leptin and Ghrelin in obese women. Methods: A sample of 40 healthy obese women with body mass index BMI≥30 were selected through stratified sampling method. They were randomly assigned to four groups of nonlinear resistance training, Spirulina supplement, nonlinear resistance training + Spirulina supplementation and Placebo (n=10). Interventions were done for 8 weeks. 24 hours before and 48 hours after the end of the interventions, blood samples were taken from all four groups in a 12-hour fasting state. For each sample, leptin and Ghrelin serum levels were measured by ELISA method. The nonlinear resistance training program included exercising weight training at varying intensity, with emphasis on muscular endurance. Supplements and placebo daily consumed 2 capsules of 500 mg of Spirulina or starch. In order to compare and evaluate the variables in four groups of research and in two blood sampling times, the inter-interstitial analysis of variance analysis was used in a 4 × 2 test and the Tukey's test was used to find means that are significantly different from each other. Results: There was no significant change in the level of Ghrelin. Leptin levels decreased significantly in the two groups nonlinear resistance training + Spirulina supplementation and nonlinear resistance compared to the other two groups. There was no significant difference between the variables of the two nonlinear resistance training + Spirulina supplementation and nonlinear resistance training groups and between the variables of the two groups of Spirulina and placebo. Conclusions: Probably eight weeks of nonlinear resistance training will lead to improved fat metabolism in overweight and obesity-related diseases such as heart disease and diabetes in obese women.

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