@article { author = {Rahim Pour, Rahim and Mehrabani, Javad}, title = {The effect of treadmill aerobic training on adipolin, glucose and insulin in type 2 diabetic male rats}, journal = {Journal of Applied Health Studies in Sport Physiology}, volume = {5}, number = {1}, pages = {93-105}, year = {2018}, publisher = {Azarbaijan Shahid Madani University}, issn = {2676-6507}, eissn = {2676-6507}, doi = {10.22049/jassp.2019.26571.1238}, abstract = {Background and objective: Secretion of pro-inflammatory and anti-inflammatory cytokines play a critical role in the regulation of metabolic conditions. This study examines the effect of eight weeks aerobic training on Adipolin cytokine and insulin resistance index in type 2 diabetic male rats.Materials and procedures: Eighteen 8-10 weeks Wister rats with 200-220 gr are selected and they divided equaly into two diabetes [DBT] and control [CON] groups randomly. The training program includes 8 weeks of endurance training on a treadmill at a constant dip of 5%. The speed started from 10 meters per minute and it rised to the 25 meters per minute and its time started from 15 minutes to 45 minutes. In end of 8 weeks training, blood samples were taken after 12 hours of fasting in order to determination of insulin, glucose and Adipulin levels. The homeostatic model assessment [HOMA] was calculated as insulin resistance index. The data were analyzed using the an independent t test. Findings: Comparisons of two groups showed that a meaningful increase in Adipulin and decrease in glucose and insulin resistance.Conclusion: According to the findings, it seems that aerobic training with moderate intensity will lead to decreasing in insulin resistance and increase in serum levels of Adipulin in type 2 diabetic rats.}, keywords = {aerobic training,Adipolin,Insulin resistance,Type 2 diabetes}, title_fa = {اثر تمرین هوازی روی تردمیل بر سطوح آدیپولین، گلوکز و انسولین در رت‌‌های نر دیابتی نوع 2}, abstract_fa = {Secretion of pro-inflammatory and anti-inflammatory cytokines play a critical role in the regulation of metabolic conditions. This study examines the effect of eight weeks aerobic training on Adipolin cytokine and insulin resistance index in type 2 diabetic male rats.Eighteen 8-10 weeks Wister rats with 200-220 gr are selected and they divided equaly into two diabetes [DBT] and control [CON] groups randomly. The training program includes 8 weeks of endurance training on a treadmill at a constant dip of 5%. The speed started from 10 meters per minute and it rised to the 25 meters per minute and its time started from 15 minutes to 45 minutes. In end of 8 weeks training, blood samples were taken after 12 hours of fasting in order to determination of insulin, glucose and Adipulin levels. The homeostatic model assessment [HOMA] was calculated as insulin resistance index. The data were analyzed using the an independent t test with the SPSS software ver. 16. A meaningful increase was observed in adipolin (1.36±0.054 vs. 1.11±0.065 ng/ml; p=0.002), and decrease in glucose (276.88±27.59 vs. 324.55±16.04 mg/dl; p=0.001), insulin (0.206±0.02 vs. 0.235±0.02 mU/l; p=0.033) and insulin resistance (2.55±0.495 vs. 3.40±0.468 mg/dl; p=0.002).According to the findings, it seems that aerobic training with moderate intensity will lead to decreasing in insulin resistance and increase in serum levels of Adipulin in type 2 diabetic rats.}, keywords_fa = {تمرین هوازی,آدیپولین,مقاومت به انسولین,دیابت نوع 2}, url = {http://jahssp.azaruniv.ac.ir/article_13926.html}, eprint = {http://jahssp.azaruniv.ac.ir/article_13926_1de5f0f247bf364a30f91479d808e2f8.pdf} }